1. A 56-year-old woman with well-controlled HIV on TDF, 3TC, and DTG is brought to the hospital by her family members because she is confused. Her vital signs are notable for BP 76/40, HR 156, RR 32, T 38.4 ̊C. Collateral history reveals that she com- plained of burning urine and back pain 1 day ago. Physical exam reveals severe tenderness on deep palpation at the costophrenic angles bilaterally. She appears septic. Which of the following interventions should be prioritized?